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St. Mary of the Barrens is a historic church and cathedral in Perryville, Missouri, offering a sacred space for worship, prayer, and spiritual reflection. As home to the National Shrine of Our Lady of the Miraculous Medal, this beautiful Catholic church welcomes pilgrims and visitors to experience the peaceful Votive Light Sanctuary, where candles burn as symbols of devotion and prayer intentions. The cathedral provides a serene environment for those seeking spiritual guidance, attending Mass, or visiting one of Missouri's most cherished religious landmarks. Whether you're a local parishioner or traveling pilgrim, St. Mary of the Barrens in Perryville offers a meaningful destination for faith, prayer, and connection with Catholic tradition.






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